Still a long way to go to achieve multidisciplinarity for the benefit of patients: commentary on the ESMO position paper (Annals of Oncology 25(1): 9-15, 2014).

نویسندگان

  • V Valentini
  • P-A Abrahamsson
  • S K Aranda
  • A Astier
  • R A Audisio
  • M Boniol
  • L Bonomo
  • A Brunelli
  • B Bultz
  • A Chiti
  • F De Lorenzo
  • J G Eriksen
  • V Goh
  • M K Gospodarowicz
  • L Grassi
  • J Kelly
  • R D Kortmann
  • T Kutluk
  • A Plate
  • G Poston
  • T Saarto
  • R Soffietti
  • A Torresin
  • W H van Harten
  • J F Verzijlbergen
  • C von Kalle
  • P Poortmans
چکیده

Under this light, it is worrisome that roughly 80% of patients included in our cohort received this treatment (and were exposed to the risk of treatment-related side-effects) without any benefits in terms of cancer-specific survival at 8-year follow-up [2]. These observations have also profound implications in terms of expenditures for the health care system. Indeed, the adoption of IMRT resulted in excess spending of $282 million per year compared with 3D conformal radiation therapy in the United States alone [5]. These increased costs did not translate into a survival benefit in the majority of patients. Taken together, these considerations reveal that the availability of a novel advanced treatment modality, such as IMRT, does not mean that all the patients will benefit from this approach. Identifying which patient represents the ideal candidate for which treatment currently remains one of the main challenges in the context of PCa. This would ultimately allow us to avoid overtreatment of a considerable proportion of patients. Additionally, this would result in substantial savings for the health care system. Well-designed prospective randomized trials with long-term follow-up are needed to finally address this issue.

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عنوان ژورنال:
  • Annals of oncology : official journal of the European Society for Medical Oncology

دوره 25 9  شماره 

صفحات  -

تاریخ انتشار 2014